Unlike germline sequencing, which analyzes the DNA in germline cells (sperm and egg cells), targeted somatic sequencing aims to investigate genetic alterations specific to an individual's non-reproductive cells. This approach is often used in cancer research and clinical diagnostics to identify somatic mutations or alterations that contribute to the development and progression of cancer. Targeted somatic sequencing allows researchers and clinicians to identify specific genetic alterations that may drive the development of cancer or other diseases. This information can be used for cancer diagnosis, prognosis, treatment selection, and monitoring of treatment response. It also provides valuable insights into the genetic landscape of tumors, helping to uncover potential therapeutic targets and guiding the development of personalized medicine approaches in oncology.
- Support for RNA/DNA/TMB/MSI/ Expression analysis
- Dedicated somatic CNV caller with 99.9 percent sensitivity
- Use any hybrid cap assay- we can help design
- Automated AMP classification with FDA and NCCN integration
- ML based variant classification
- ITD support in complex regions
- Large Indel support